OKLAHOMA CITY — Tornadoes destroyed homes, overturned vehicles and stripped the bark from trees as they churned across Oklahoma, part of a strong series of storms that hit the Plains.

At least two people died Monday in weather so violent that forecasters declared a “tornado emergency” for communities in the path of one of the twisters. The Storm Prediction Center said 23 tornadoes were reported across five states.

“You are in a life-threatening situation,” forecasters declared while warning the communities of Roff, population 725, and Hickory, population 71, which were ultimately spared major damage. “Flying debris will be deadly to those caught without shelter.”

Dana Lance was driving through the community of Roff, about 85 miles southeast of Oklahoma City, on her way home from work Monday when the skies grew ominous, sirens wailed and forecasters on the radio told people to take cover. “I parked and went into the school, which has a safe room,” Lance said. “There were kids and elderly people, dogs and cats, babies. It was like the whole town was there.”

In nearby Murray County, where Hickory is located, emergency management director Gary Ligon said one person was injured.

Garvin County officials said a man believed to be in his upper 70s died when another tornado hit a home near Wynnewood, south of Oklahoma City. That storm, caught on video by several storm chasers, appeared white against the dark clouds of a supercell storm. In Johnston County, the sheriff’s office said a man was killed by a tornado near Connerville.

The Oklahoma Office of Emergency Management reported the storms destroyed a radio station building in Coal County and an undetermined number of homes in Murray, Garvin and Johnston counties.

The bad weather should settle Tuesday in the Ohio and Tennessee valleys, where hail, strong winds and tornadoes are possible. A separate system is poised to move through north Texas, including the Dallas-Fort Worth area. In all, about 44 million people live in areas that could see storms Tuesday, the Storm Prediction Center said.

Another storm system should bring storms to the area from north Texas to near St. Louis on Wednesday.

In Hugo, Oklahoma, near the Red River, Charles Webb piled one of his dogs and one of his cats in the laundry room Monday and hunkered down as the storm came over his house, clipping trees and spinning up debris. Webb said he emerged from his home minutes later to see blue skies.

“We’re real lucky, but we’ve been lucky for a lot of years, fortunately,” Webb said Monday.

In the rolling hills between Oklahoma City and Dallas, the Oklahoma Highway Patrol closed Interstate 35 near Wynnewood for 15 minutes Monday so the storm could pass.