SALEM, N.H. — Eyeing their first wins in a capricious campaign, Republican Donald Trump lashed out at his opponents Monday while Democrat Bernie Sanders sought to play it safe on the eve of the nation’s initial primary. GOP contenders vying for second and third saw fresh hopes for survival after New Hampshire as both parties settled in for a drawn-out slog to the nomination.

As snowfall brought yet more uncertainty to the race’s final hours, Hillary Clinton tried to move past talk of a shakeup in her campaign and controversy over comments by supporters that women should feel obliged to vote for her. Barnstorming New Hampshire with her husband and daughter, she worked to flip Sanders’ favored critique against her by claiming that he, too, had taken big bucks from Wall Street — if only indirectly.

But it was Trump, the billionaire businessman, who launched the harshest attacks — not just against Texas Sen. Ted Cruz, who had bested him in Iowa, but against Jeb Bush as well. The former Florida governor is one of three Republicans hoping Marco Rubio’s recent stumbles have opened a fresh path for one of them to emerge as the more mainstream alternative to Trump and Cruz.

“Jeb is having some kind of a breakdown, I think,” Trump told CNN, calling Bush, the son and brother of presidents, a spoiled child and an embarrassment to his family. “I think it’s a very sad situation that’s taking place.”

The enmity was mutual. Vying for votes in Nashua, Bush described his opponent variably as a loser, a liar, a whiner and the worst choice for president. He blasted what he said was Trump’s proclivity for “insulting women, castigating Hispanics, ridiculing the disabled and calling American POWs losers.”

Trump did get in a shot at Cruz during a massive rally in Manchester Monday night. When an audience member shouted out an insult directed at Cruz — a vulgar term for “coward” — Trump repeated the term and jokingly reprimanded the woman.

Cruz spokesman Rick Tyler responded via email, saying, “Let’s not forget who whipped who in Iowa.”